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Using Sequence-Specific Chemical and Structural Properties of DNA to Predict Transcription Factor Binding Sites

An important step in understanding gene regulation is to identify the DNA binding sites recognized by each transcription factor (TF). Conventional approaches to prediction of TF binding sites involve the definition of consensus sequences or position-specific weight matrices and rely on statistical a...

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Detalhes bibliográficos
Main Authors: Bauer, Amy L., Hlavacek, William S., Unkefer, Pat J., Mu, Fangping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987836/
https://ncbi.nlm.nih.gov/pubmed/21124945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001007
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