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Improved predictions of transcription factor binding sites using physicochemical features of DNA

Typical approaches for predicting transcription factor binding sites (TFBSs) involve use of a position-specific weight matrix (PWM) to statistically characterize the sequences of the known sites. Recently, an alternative physicochemical approach, called SiteSleuth, was proposed. In this approach, a...

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Detalhes bibliográficos
Main Authors: Maienschein-Cline, Mark, Dinner, Aaron R., Hlavacek, William S., Mu, Fangping
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526315/
https://ncbi.nlm.nih.gov/pubmed/22923524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks771
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