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A flexible integrative approach based on random forest improves prediction of transcription factor binding sites

Transcription factor binding sites (TFBSs) are DNA sequences of 6–15 base pairs. Interaction of these TFBSs with transcription factors (TFs) is largely responsible for most spatiotemporal gene expression patterns. Here, we evaluate to what extent sequence-based prediction of TFBSs can be improved by...

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Detalhes bibliográficos
Main Authors: Hooghe, Bart, Broos, Stefan, van Roy, Frans, De Bleser, Pieter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413102/
https://ncbi.nlm.nih.gov/pubmed/22492513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks283
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