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PhysBinder: improving the prediction of transcription factor binding sites by flexible inclusion of biophysical properties

The most important mechanism in the regulation of transcription is the binding of a transcription factor (TF) to a DNA sequence called the TF binding site (TFBS). Most binding sites are short and degenerate, which makes predictions based on their primary sequence alone somewhat unreliable. We presen...

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Bibliografiske detaljer
Main Authors: Broos, Stefan, Soete, Arne, Hooghe, Bart, Moran, Raymond, van Roy, Frans, De Bleser, Pieter
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692127/
https://ncbi.nlm.nih.gov/pubmed/23620286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt288
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