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PhysBinder: improving the prediction of transcription factor binding sites by flexible inclusion of biophysical properties
The most important mechanism in the regulation of transcription is the binding of a transcription factor (TF) to a DNA sequence called the TF binding site (TFBS). Most binding sites are short and degenerate, which makes predictions based on their primary sequence alone somewhat unreliable. We presen...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3692127/ https://ncbi.nlm.nih.gov/pubmed/23620286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt288 |
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