Differential Subcellular Recruitment of Monoacylglycerol Lipase Generates Spatial Specificity of 2-Arachidonoyl Glycerol Signaling during Axonal Pathfinding

Endocannabinoids, particularly 2-arachidonoyl glycerol (2-AG), impact the directional turning and motility of a developing axon by activating CB(1) cannabinoid receptors (CB(1)Rs) in its growth cone. Recent findings posit that sn-1-diacylglycerol lipases (DAGLα/β) synthesize 2-AG in the motile axon...

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Huvudupphovsmän: Keimpema, Erik, Barabas, Klaudia, Morozov, Yury M., Tortoriello, Giuseppe, Torii, Masaaki, Cameron, Gary, Yanagawa, Yuchio, Watanabe, Masahiko, Mackie, Ken, Harkany, Tibor
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2010
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987617/
https://ncbi.nlm.nih.gov/pubmed/20962221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2126-10.2010
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