Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis

Oxidation products of low-density lipoproteins have been suggested to promote inflammation during atherogenesis, and reticulocyte-type 15-lipoxygenase has been implicated to mediate this oxidation. In addition, the 5-lipoxygenase cascade leads to formation of leukotrienes, which exhibit strong proin...

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Bibliographic Details
Main Authors: Spanbroek, Rainer, Gräbner, Rolf, Lötzer, Katharina, Hildner, Markus, Urbach, Anja, Rühling, Katharina, Moos, Michael P. W., Kaiser, Brigitte, Cohnert, Tina U., Wahlers, Thorsten, Zieske, Arthur, Plenz, Gabriele, Robenek, Horst, Salbach, Peter, Kühn, Hartmut, Rådmark, Olof, Samuelsson, Bengt, Habenicht, Andreas J. R.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC298757/
https://ncbi.nlm.nih.gov/pubmed/12552108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242716099
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