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Sporadic cases are the norm for complex disease
The results of genome-wide association studies have revealed that most human complex diseases (for example, cancer, diabetes and psychiatric disorders) are affected by a large number of variants, each of which explains a small increase in disease risk, suggesting a pattern of polygenic inheritance....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2987426/ https://ncbi.nlm.nih.gov/pubmed/19826454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2009.177 |
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