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The Genetic Interpretation of Area under the ROC Curve in Genomic Profiling

Genome-wide association studies in human populations have facilitated the creation of genomic profiles which combine the effects of many associated genetic variants to predict risk of disease. The area under the receiver operator characteristic (ROC) curve is a well established measure for determini...

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Detalhes bibliográficos
Main Authors: Wray, Naomi R., Yang, Jian, Goddard, Michael E., Visscher, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829056/
https://ncbi.nlm.nih.gov/pubmed/20195508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000864
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