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The Genetic Interpretation of Area under the ROC Curve in Genomic Profiling

Genome-wide association studies in human populations have facilitated the creation of genomic profiles which combine the effects of many associated genetic variants to predict risk of disease. The area under the receiver operator characteristic (ROC) curve is a well established measure for determini...

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Autori principali: Wray, Naomi R., Yang, Jian, Goddard, Michael E., Visscher, Peter M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829056/
https://ncbi.nlm.nih.gov/pubmed/20195508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000864
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