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The contribution of genetic variants to disease depends on the ruler
Our understanding of the genetic basis of disease has evolved from descriptions of overall heritability or familiality to identifying large numbers of risk loci. One can quantify the impact of such loci on disease using a plethora of measures, which can guide decisions on new experiments, for exampl...
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Publicado no: | Nat Rev Genet |
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Principais autores: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4412738/ https://ncbi.nlm.nih.gov/pubmed/25223781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3786 |
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