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Linkage disequilibrium and age of HLA region SNPs in relation to classic HLA gene alleles within Europe
The HLA region on chromosome 6 is gene-rich and under selective pressure because of the high proportion of immunity-related genes. Linkage disequilibrium (LD) patterns and allele frequencies in this region are highly differentiated across broad geographical populations, making it a region of interes...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2987379/ https://ncbi.nlm.nih.gov/pubmed/20354563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.32 |
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