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Linkage disequilibrium and age of HLA region SNPs in relation to classic HLA gene alleles within Europe

The HLA region on chromosome 6 is gene-rich and under selective pressure because of the high proportion of immunity-related genes. Linkage disequilibrium (LD) patterns and allele frequencies in this region are highly differentiated across broad geographical populations, making it a region of interes...

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Detalhes bibliográficos
Main Authors: Evseeva, Irina, Nicodemus, Kristin K, Bonilla, Carolina, Tonks, Susan, Bodmer, Walter F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987379/
https://ncbi.nlm.nih.gov/pubmed/20354563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.32
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