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Multiple mutations and cancer
Most human tumors are highly heterogenous. We have hypothesized that this heterogeneity results from a mutator phenotype. Our premise is that normal mutation rates are insufficient to account for the multiple mutations found in human cancers, and, instead, that cancers must exhibit a mutator phenoty...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The National Academy of Sciences
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC298677/ https://ncbi.nlm.nih.gov/pubmed/12552134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0334858100 |
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