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Human longevity and 11p15.5: a study in 1321 centenarians

The 11p15.5 chromosomal region (2.8 Mb) is of particular interest as it encloses five genes (HRAS1, SIRT3, TH, INS and IGF2), the variability of which was found to be associated with life extension by association studies. Mostly important, the above genes are homologous of genes that modulate lifesp...

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Detalhes bibliográficos
Main Authors: Lescai, Francesco, Blanché, Helene, Nebel, Almut, Beekman, Marian, Sahbatou, Mourad, Flachsbart, Friederike, Slagboom, Eline, Schreiber, Stefan, Sorbi, Sandro, Passarino, Giuseppe, Franceschi, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2986679/
https://ncbi.nlm.nih.gov/pubmed/19367319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2009.54
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