A humanized antibody that binds to the interleukin 2 receptor.

The anti-Tac monoclonal antibody is known to bind to the p55 chain of the human interleukin 2 receptor and to inhibit proliferation of T cells by blocking interleukin 2 binding. However, use of anti-Tac as an immunosuppressant drug would be impaired by the human immune response against this murine a...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Queen, C, Schneider, W P, Selick, H E, Payne, P W, Landolfi, N F, Duncan, J F, Avdalovic, N M, Levitt, M, Junghans, R P, Waldmann, T A
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1989
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298637/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2513570/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.10029
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