A humanized antibody that binds to the interleukin 2 receptor.
The anti-Tac monoclonal antibody is known to bind to the p55 chain of the human interleukin 2 receptor and to inhibit proliferation of T cells by blocking interleukin 2 binding. However, use of anti-Tac as an immunosuppressant drug would be impaired by the human immune response against this murine a...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1989
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298637/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2513570/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.10029 |
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