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A humanized antibody that binds to the interleukin 2 receptor.

The anti-Tac monoclonal antibody is known to bind to the p55 chain of the human interleukin 2 receptor and to inhibit proliferation of T cells by blocking interleukin 2 binding. However, use of anti-Tac as an immunosuppressant drug would be impaired by the human immune response against this murine a...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Queen, C, Schneider, W P, Selick, H E, Payne, P W, Landolfi, N F, Duncan, J F, Avdalovic, N M, Levitt, M, Junghans, R P, Waldmann, T A
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1989
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298637/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2513570/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.10029
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