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SNP frequency estimation using massively parallel sequencing of pooled DNA

Resequencing of genomic regions that have been implicated by linkage and/or association studies to harbor genetic susceptibility loci represents a necessary step to identify causal variants. Massively parallel sequencing (MPS) offers the possibility of SNP discovery and frequency determination among...

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Detalhes bibliográficos
Main Authors: Ingman, Max, Gyllensten, Ulf
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2986170/
https://ncbi.nlm.nih.gov/pubmed/18854868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2008.182
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