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Initiation of transcription on nucleosomal templates.

We describe a simple method that uses curved DNAs to move nucleosomes relative to a sequence of interest. With this method, small changes in the association of a T7 RNA polymerase promoter with a nucleosome are shown to lead to significant changes in transcription efficiency.

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Detalhes bibliográficos
Main Authors: Wolffe, A P, Drew, H R
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC298593/
https://ncbi.nlm.nih.gov/pubmed/2690074
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