Initiation of transcription on nucleosomal templates.
We describe a simple method that uses curved DNAs to move nucleosomes relative to a sequence of interest. With this method, small changes in the association of a T7 RNA polymerase promoter with a nucleosome are shown to lead to significant changes in transcription efficiency. IMAGES:
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1989
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298593/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2690074/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.9817 |
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