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Initiation of transcription on nucleosomal templates.

We describe a simple method that uses curved DNAs to move nucleosomes relative to a sequence of interest. With this method, small changes in the association of a T7 RNA polymerase promoter with a nucleosome are shown to lead to significant changes in transcription efficiency. IMAGES:

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Wolffe, A P, Drew, H R
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1989
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298593/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2690074/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.9817
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