DNA and spermidine provide a switch mechanism to regulate the activity of restriction enzyme Nae I.
Sequence-specific DNA-protein interactions are basic to DNA function. To better understand these interactions, we studied the effect of position on cleavage of DNA by the type II restriction enzyme (EC 3.1.21.4) Nae I. We discovered two classes of Nae I restriction sites: sites susceptible and sites...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298570/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2602372/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.9707 |
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