Structural basis of protein kinase C activation by tumor promoters.

Protein kinase C (PKC) is an important enzyme that helps govern cell metabolism and growth. The enzyme is physiologically activated when an (S)-diglyceride binds to its own regulatory domain. The saturable binding site of the regulatory domain can also be bound by any of a group of structurally dive...

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Bibliographic Details
Main Authors: Nakamura, H, Kishi, Y, Pajares, M A, Rando, R R
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC298563/
https://ncbi.nlm.nih.gov/pubmed/2602368
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