Prevention of experimental encephalomyelitis with peptides that block interaction of T cells with major histocompatibility complex proteins.
Two synthetic immunodominant and nonencephalitogenic peptides of myelin basic protein, N1-20 and AcN9-20, effectively compete with an encephalitogenic peptide, AcN1-11, in an in vitro T-cell response restricted by class II major histocompatibility complex products (I-Au). These mutant peptide constr...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1989
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298518/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2480602/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.23.9470 |
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