Prevention of experimental encephalomyelitis with peptides that block interaction of T cells with major histocompatibility complex proteins.

Two synthetic immunodominant and nonencephalitogenic peptides of myelin basic protein, N1-20 and AcN9-20, effectively compete with an encephalitogenic peptide, AcN1-11, in an in vitro T-cell response restricted by class II major histocompatibility complex products (I-Au). These mutant peptide constr...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sakai, K, Zamvil, S S, Mitchell, D J, Hodgkinson, S, Rothbard, J B, Steinman, L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298518/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2480602/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.23.9470
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