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Specific gene suppression by engineered ribozymes in monkey cells.

Short catalytic RNAs possessing specific endoribonuclease activity (ribozymes) have recently been designed that can potentially shear any chosen target RNA in trans at a specific site. Here, engineered ribozymes targeted against chloramphenicol acetyltransferase (CAT), derived from Tn9, have been cl...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Cameron, F H, Jennings, P A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298449/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2556702/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.23.9139
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