Use of an engineered ribozyme to produce a circular human exon.

We report the use of an engineered ribozyme to produce a circular human exon in vitro. Specifically, we have designed a derivative of a yeast self-splicing group II intron that is able to catalyze the formation of a circular exon encoding the first kringle domain (K1) of the human tissue plasminogen...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Mikheeva, S, Hakim-Zargar, M, Carlson, D, Jarrell, K
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147139/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9396820/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.24.5085
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