Specific gene suppression by engineered ribozymes in monkey cells.
Short catalytic RNAs possessing specific endoribonuclease activity (ribozymes) have recently been designed that can potentially shear any chosen target RNA in trans at a specific site. Here, engineered ribozymes targeted against chloramphenicol acetyltransferase (CAT), derived from Tn9, have been cl...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1989
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298449/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2556702/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.23.9139 |
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