Use of an engineered ribozyme to produce a circular human exon.
We report the use of an engineered ribozyme to produce a circular human exon in vitro. Specifically, we have designed a derivative of a yeast self-splicing group II intron that is able to catalyze the formation of a circular exon encoding the first kringle domain (K1) of the human tissue plasminogen...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1997
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147139/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9396820/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.24.5085 |
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