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Water’s role in the force-induced unfolding of ubiquitin

In atomic force spectroscopic studies of the elastomeric protein ubiquitin, the β-strands 1-5 serve as the force clamp. Simulations show how the rupture force in the force-induced unfolding depends on the kinetics of water molecule insertion into positions where they can eventually form hydrogen bon...

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Autori principali: Li, Jingyuan, Fernandez, Julio M., Berne, B. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984199/
https://ncbi.nlm.nih.gov/pubmed/20974922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013159107
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