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Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation
DNase II digests the chromosomal DNA in macrophages after apoptotic cells and nuclei from erythroid precursors are engulfed. The DNase II-null mice develop a polyarthritis that resembles rheumatoid arthritis. Here, we showed that when bone marrow cells from the DNase II-deficient mice were transferr...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2984163/ https://ncbi.nlm.nih.gov/pubmed/20974942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010603107 |
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