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Activation of the innate immunity in Drosophila by endogenous chromosomal DNA that escaped apoptotic degradation
Apoptotic cell death is accompanied by degradation of chromosomal DNA. Here, we established in Drosophila a null mutation in the gene for inhibitor of caspase-activated DNase (ICAD) by P-element insertion. We also identified a loss-of-function mutant in Drosophila for DNase II-like acid DNase. The f...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC187462/ https://ncbi.nlm.nih.gov/pubmed/12381665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1022802 |
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