Horizontal transfer of penicillin-binding protein genes in penicillin-resistant clinical isolates of Streptococcus pneumoniae.
Resistance to penicillin in clinical isolates of Streptococcus pneumoniae has occurred by the development of altered penicillin-binding proteins (PBPs) that have greatly decreased affinity for the antibiotic. We have investigated the origins of penicillin-resistant strains by comparing the sequences...
Guardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1989
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298386/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2813426/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.22.8842 |
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