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Horizontal transfer of penicillin-binding protein genes in penicillin-resistant clinical isolates of Streptococcus pneumoniae.

Resistance to penicillin in clinical isolates of Streptococcus pneumoniae has occurred by the development of altered penicillin-binding proteins (PBPs) that have greatly decreased affinity for the antibiotic. We have investigated the origins of penicillin-resistant strains by comparing the sequences...

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Bibliografiske detaljer
Main Authors: Dowson, C G, Hutchison, A, Brannigan, J A, George, R C, Hansman, D, Liñares, J, Tomasz, A, Smith, J M, Spratt, B G
Format: Artigo
Sprog:Inglês
Udgivet: 1989
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC298386/
https://ncbi.nlm.nih.gov/pubmed/2813426
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