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Deoxycholyltaurine Rescues Human Colon Cancer Cells From Apoptosis by Activating EGFR-Dependent PI3K/Akt Signaling

Recent studies indicate that secondary bile acids promote colon cancer cell proliferation but their role in maintaining cell survival has not been explored. We found that deoxycholyltaurine (DCT) markedly attenuated both unstimulated and TNF-α-stimulated programmed cell death in colon cancer cells b...

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Detalhes bibliográficos
Main Authors: Raufman, Jean-Pierre, Shant, Jasleen, Guo, Chang Yue, Roy, Sanjit, Cheng, Kunrong
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982791/
https://ncbi.nlm.nih.gov/pubmed/18064605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21332
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