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Polypyrimidine tract-binding protein stimulates the poliovirus IRES by modulating eIF4G binding

Tethered hydroxyl-radical probing has been used to determine the orientation of binding of polypyrimidine tract-binding protein (PTB) to the poliovirus type 1 (Mahoney) (PV-1(M)) internal ribosome entry site/segment (IRES)—the question of which RNA-binding domain (RBD) binds to which sites on the IR...

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Detalhes bibliográficos
Main Authors: Kafasla, Panagiota, Morgner, Nina, Robinson, Carol V, Jackson, Richard J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982756/
https://ncbi.nlm.nih.gov/pubmed/20859255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.231
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