Polypyrimidine Tract Binding Protein Modulates Efficiency of Polyadenylation

Polypyrimidine tract binding protein (PTB) is a major hnRNP protein with multiple roles in mRNA metabolism, including regulation of alternative splicing and internal ribosome entry site-driven translation. We show here that a fourfold overexpression of PTB results in a 75% reduction of mRNA levels p...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Castelo-Branco, Pedro, Furger, Andre, Wollerton, Matthew, Smith, Christopher, Moreira, Alexandra, Proudfoot, Nick
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC400487/
https://ncbi.nlm.nih.gov/pubmed/15121839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.10.4174-4183.2004
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados