Hybrid cytochromes P-450 identify a substrate binding domain in P-450IIC5 and P-450IIC4.
The cytochrome P-450 superfamily of enzymes catalyzes the oxidative metabolism of innumerable lipophilic compounds (e.g., drugs, carcinogens, steroids). Although the three-dimensional structure of a soluble bacterial P-450 (P-450cam) has been solved, little is known about the structures of the membr...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298260/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2813390/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.21.8262 |
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