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Hybrid cytochromes P-450 identify a substrate binding domain in P-450IIC5 and P-450IIC4.

The cytochrome P-450 superfamily of enzymes catalyzes the oxidative metabolism of innumerable lipophilic compounds (e.g., drugs, carcinogens, steroids). Although the three-dimensional structure of a soluble bacterial P-450 (P-450cam) has been solved, little is known about the structures of the membr...

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Detalhes bibliográficos
Main Authors: Kronbach, T, Larabee, T M, Johnson, E F
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC298260/
https://ncbi.nlm.nih.gov/pubmed/2813390
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