Immunoglobulin double-isotype expression by trans-mRNA in a human immunoglobulin transgenic mouse.

We have studied immunoglobulin double-isotype expression in a transgenic mouse (TG.SA) in which expression of the endogenous immunoglobulin heavy chain locus is almost completely excluded by a nonallelic rearranged human mu transgene. By flow-cytometric analyses, we have shown that a small, but sign...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Shimizu, A, Nussenzweig, M C, Mizuta, T R, Leder, P, Honjo, T
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1989
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298205/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2510157/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.20.8020
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