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Applying bioinformatics for antibody epitope prediction using affinity-selected mimotopes – relevance for vaccine design

To properly characterize protective polyclonal antibody responses, it is necessary to examine epitope specificity. Most antibody epitopes are conformational in nature and, thus, cannot be identified using synthetic linear peptides. Cyclic peptides can function as mimetics of conformational epitopes...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Denisova, Galina F, Denisov, Dimitri A, Bramson, Jonathan L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981875/
https://ncbi.nlm.nih.gov/pubmed/21067548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-7580-6-S2-S6
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