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Applying bioinformatics for antibody epitope prediction using affinity-selected mimotopes – relevance for vaccine design

To properly characterize protective polyclonal antibody responses, it is necessary to examine epitope specificity. Most antibody epitopes are conformational in nature and, thus, cannot be identified using synthetic linear peptides. Cyclic peptides can function as mimetics of conformational epitopes...

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Detalhes bibliográficos
Main Authors: Denisova, Galina F, Denisov, Dimitri A, Bramson, Jonathan L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981875/
https://ncbi.nlm.nih.gov/pubmed/21067548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-7580-6-S2-S6
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