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Soluble factors from IL-1β-stimulated astrocytes activate NR1a/NR2B receptors: implications for HIV-1-induced neurodegeneration

Astrocytes play an important role in astrocyte-neuron homeostasis. In HIV-1-infected brain, interleukin 1 beta (IL-1β) activation of astrocytes contributes to neurodegeneration. However, the molecular mechanisms underlying IL-1β-activated-astrocytes-induced neurodegeneration in HIV-1-infected brain...

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Detalhes bibliográficos
Main Authors: Jing, Tao, Wu, Li, Borgmann, Kathleen, Surendran, Sankar, Ghorpade, Anuja, Liu, Jianuo, Xiong, Huangui
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981639/
https://ncbi.nlm.nih.gov/pubmed/20933498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.10.006
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