The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab

Objective. SSc is an autoimmune disease characterized by fibrosis of the skin and internal organs. Although the aetiology remains uncertain, many reports have suggested that IL-6 is involved in SSc pathogenesis. Tocilizumab, an anti-IL-6 receptor antibody, is an anti-arthritis medicine that works th...

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Detalles Bibliográficos
Autores principales: Shima, Yoshihito, Kuwahara, Yusuke, Murota, Hiroyuki, Kitaba, Shun, Kawai, Mari, Hirano, Toru, Arimitsu, Junsuke, Narazaki, Masashi, Hagihara, Keisuke, Ogata, Atsushi, Katayama, Ichiro, Kawase, Ichiro, Kishimoto, Tadamitsu, Tanaka, Toshio
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
Materias:
Clinical Science
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981510/
https://ncbi.nlm.nih.gov/pubmed/20819796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/keq275
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