Mycobacterium tuberculosis Synergizes with ATP To Induce Release of Microvesicles and Exosomes Containing Major Histocompatibility Complex Class II Molecules Capable of Antigen Presentation

Major histocompatibility complex class II (MHC-II) molecules are released by murine macrophages upon lipopolysaccharide (LPS) stimulation and ATP signaling through the P2X7 receptor. These studies show that infection of macrophages with Mycobacterium tuberculosis or M. bovis strain BCG enhances MHC-...

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Bibliographische Detailangaben
Hauptverfasser: Ramachandra, Lakshmi, Qu, Yan, Wang, Ying, Lewis, Colleen J., Cobb, Brian A., Takatsu, Kiyoshi, Boom, W. Henry, Dubyak, George R., Harding, Clifford V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Host Response and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981298/
https://ncbi.nlm.nih.gov/pubmed/20837713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01089-09
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