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ATP and Control of Intracellular Growth of Mycobacteria by T Cells

Extracellular ATP at millimolar concentrations inhibits growth of mycobacteria in human macrophages. Whether T cells can produce sufficient ATP is unknown. CD4(+) and CD8(+) T cells did not release sufficient ATP through either degranulation or lysis of bystander cells to restrict growth of Mycobact...

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Autors principals: Canaday, David H., Beigi, Reza, Silver, Richard F., Harding, Clifford V., Boom, W. Henry, Dubyak, George R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC130300/
https://ncbi.nlm.nih.gov/pubmed/12379727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.11.6456-6459.2002
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