Oritavancin Disrupts Membrane Integrity of Staphylococcus aureus and Vancomycin-Resistant Enterococci To Effect Rapid Bacterial Killing

Oritavancin is an investigational lipoglycopeptide in clinical development for the treatment of acute bacterial skin and skin structure infections. In this study, we demonstrate that oritavancin causes bacterial membrane depolarization and permeabilization leading to cell death of Gram-positive path...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Belley, Adam, McKay, Geoffrey A., Arhin, Francis F., Sarmiento, Ingrid, Beaulieu, Sylvain, Fadhil, Ibthihal, Parr, Thomas R., Moeck, Gregory
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Materias:
Mechanisms of Action: Physiological Effects
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981232/
https://ncbi.nlm.nih.gov/pubmed/20876372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00760-10
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares