Oritavancin Disrupts Membrane Integrity of Staphylococcus aureus and Vancomycin-Resistant Enterococci To Effect Rapid Bacterial Killing

Oritavancin is an investigational lipoglycopeptide in clinical development for the treatment of acute bacterial skin and skin structure infections. In this study, we demonstrate that oritavancin causes bacterial membrane depolarization and permeabilization leading to cell death of Gram-positive path...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Belley, Adam, McKay, Geoffrey A., Arhin, Francis F., Sarmiento, Ingrid, Beaulieu, Sylvain, Fadhil, Ibthihal, Parr, Thomas R., Moeck, Gregory
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981232/
https://ncbi.nlm.nih.gov/pubmed/20876372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00760-10
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados