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Assessment of Oritavancin Serum Protein Binding across Species

Biophysical methods to study the binding of oritavancin, a lipoglycopeptide, to serum protein are confounded by nonspecific drug adsorption to labware surfaces. We assessed oritavancin binding to serum from mouse, rat, dog, and human by a microbiological growth-based method under conditions that all...

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主要な著者: Arhin, Francis F., Belley, Adam, McKay, Geoffrey, Beaulieu, Sylvain, Sarmiento, Ingrid, Parr, Thomas R., Moeck, Gregory
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2010
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916308/
https://ncbi.nlm.nih.gov/pubmed/20498314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00271-10
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