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Assessment of Oritavancin Serum Protein Binding across Species
Biophysical methods to study the binding of oritavancin, a lipoglycopeptide, to serum protein are confounded by nonspecific drug adsorption to labware surfaces. We assessed oritavancin binding to serum from mouse, rat, dog, and human by a microbiological growth-based method under conditions that all...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916308/ https://ncbi.nlm.nih.gov/pubmed/20498314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00271-10 |
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