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Upf1 senses 3′UTR length to potentiate mRNA decay

The selective degradation of mRNAs by the nonsense-mediated decay pathway is a quality control process with important consequences for human disease. From initial studies using RNA hairpin-tagged mRNAs for purification of messenger ribonucleoproteins assembled on transcripts with HIV-1 3′ untranslat...

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Bibliografske podrobnosti
Main Authors: Hogg, J. Robert, Goff, Stephen P.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981159/
https://ncbi.nlm.nih.gov/pubmed/21029861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.10.005
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