Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells.

We have analyzed the modulation of amyloid beta-protein precursor (APP) gene expression in human umbilical vein endothelial cells (HUVEC). The level of the APP mRNA transcripts increased as HUVEC reached confluency. In confluent culture the half-life of the APP mRNA was 4 hr. Treatment of the cells...

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Main Authors: Goldgaber, D, Harris, H W, Hla, T, Maciag, T, Donnelly, R J, Jacobsen, J S, Vitek, M P, Gajdusek, D C
格式: Artigo
語言:Inglês
出版: 1989
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC298115/
https://ncbi.nlm.nih.gov/pubmed/2508093
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